Blar i forfatter "Bussel, James B."

Viser treff 1-2 av 2

    • Fetal/neonatal alloimmune thrombocytopenia: A systematic review of impact of HLA-DRB3∗01:01 on fetal/neonatal outcome 

      Kjeldsen-Kragh, Jens; Fergusson, Dean; Kjær, Mette; Lieberman, Lani; Greinacher, Andreas; Murphy, Michael F.; Bussel, James B.; Bakchoul, Tamam; Corke, Stacy; Bertrand, Gerald; Oepkes, Dick; Baker, Jillian M.; Hume, Heather; Massey, Edwin; Kaplan, Cecile; Arnold, Donald M.; Baidya, Shoma; Ryan, Greg; Savoia, Helen; Landry, Denise; Shehata, Nadine (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-27)
      The most common, severe cases of fetal and neonatal alloimmune thrombocytopenia among whites are caused by antibodies against human platelet antigen 1a (HPA-1a). The aims of this systematic review and meta-analysis are to determine the association between maternal HLA-DRB3*01:01 and: (1) HPA-1a-alloimmunization and (2) neonatal outcome in children born of HPA-1a-immunized women. A systematic ...

    • Strategies to develop a prophylaxis for the prevention of HPA-1a immunization and fetal and neonatal alloimmune thrombocytopenia 

      Kjær, Mette; Geisen, Christof; Akkøk, Cigdem Ahaein; Wikman, Agneta; Sachs, Ulrich; Bussel, James B.; Nielsen, Kaspar; Walles, Katarina; Curtis, Brian R.; Vidarsson, Gestur; Järås, Kerstin; Skogen, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-31)
      Anti-HPA-1a-antibodies are the main cause of fetal and neonatal alloimmune thrombocytopenia (FNAIT) which may result in intracranial hemorrhage (ICH) and death among fetuses and newborns. Advances in understanding the pathogenesis of FNAIT and proof of concept for prophylaxis to prevent immunization suggest that development of hyperimmune anti-HPA-1a IgG aimed at preventing immunization against ...